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. Author manuscript; available in PMC: 2022 Jan 19.
Published in final edited form as: J Mol Cell Cardiol. 2021 Sep 3;162:32–42. doi: 10.1016/j.yjmcc.2021.08.013

Fig. 1.

Fig. 1.

Glucose-derived amphibolic metabolites and biosynthetic pathway enrichment. Metabolic network map highlighting potential modes of glucose utilization and branchpoint intermediates (bolded) which could influence the balance between catabolism and anabolism within a cell. Asp = aspartate, UMP = uridine monophosphate, UDP = uridine diphosphate, Glc = glucose, G1P = glucose-1-phosphate, G6P = glucose-6-phosphate, 6PG = 6-phosphogluconate, Ru5P = ribulose-5-phosphate, R5P = ribose-5-phosphate, PRPP = phosphoribosyl pyrophosphate, AICAR = 5-aminoimidazole-4-carboxamide ribonucleotide, IMP = inosine monophosphate, GMP = guanosine monophosphate, AMP = adenosine monophosphate, F6P = fructose-6-phosphate, FBP = fructose-1,6-bisphosphate, PFK = phosphofructokinase, X5P = xylulose-5-phosphate, GAP = glyceraldehyde-3-phosphate, S7P = seduheptulose-7-phosphate, E4P = erythrose-4-phosphate, DHAP = dihydroxyacetone phosphate, 3PG = 3-phosphoglycerate, TCA = tricarboxylic acid cycle.