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. Author manuscript; available in PMC: 2023 Jan 1.
Published in final edited form as: Circ Arrhythm Electrophysiol. 2021 Dec 29;15(1):e010365. doi: 10.1161/CIRCEP.121.010365

Figure 3. Dependence of P2R on heart rate and late Ito.

Figure 3.

1D cable simulations with periodic or random pacing from the endocardium. A. Percentage of beats exhibiting PVCs versus Gto and PCL under periodic pacing for γ = 0, γ = 0.02, and γ = 0.05. 200 pacing beats were applied for each combination of Gto and PCL. Color scale indicates the percentage of PVC beats. B. Histograms showing percentage of PVC beats versus Gto for γ = 0, γ = 0.02, and γ = 0.05 under periodic pacing with PCL=1500 ms. 2000 pacing beats were applied for each Gto. C. Same as B but for the random pacing protocol with random PCLs uniformly drawn from the interval between 500 ms and 1500 ms.