Skip to main content
. 2022 Jan 5;12:801493. doi: 10.3389/fphar.2021.801493

FIGURE 3.

FIGURE 3

IL-32 promotes the metastasis of bladder cancer. (A) IL-32 enhances the migration ability of bladder cancer cells. Representative data of 3 independent experiments from wound healing migration assays performed with the indicated bladder cancer cells. Scale bar = 100 μm (left panel). The relative values of width are shown as the mean ± SD. *p < 0.05; one-way ANOVA (right panel). (B) IL-32 increases the invasion ability of bladder cancer cells. Representative data of three independent experiments from crystal violet staining showing the invasive capacities of bladder cancer cells. Scale bar = 100 μm (left panel). The number of migrated cells is shown as the mean ± SD. ***p < 0.001; one-way ANOVA (right panel). (C) IL-32 does not disrupt the proliferation of bladder cancer cells. Cell viability was measured using the CCK8 assay. Data are shown as the mean ± SD. (D) The association between IL-32 and CCL4. The relationship between IL-32 and CCL4 in the TCGA and GTEx databases is shown. Spearman’s rank correlation coefficient is shown.