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. 2022 Jan 5;8:813757. doi: 10.3389/fnut.2021.813757

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Copyright © 2022 Wu, Cheng, Wang, Feng, Zou, Tan, Yang, Wang, Zhang, Dong, Xiao, Tao and Wei.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of GF diet on intestinal morphology of SPF mice. Hematoxylin and eosin staining of (A) Duodenum, (B) Jejunum, and (C) Ileum. (D) Villus length of duodenum. (E) Villus length of jejunum, (F) Villus length of ileum, (G) Crypt length of duodenum. (H) Crypt length of jejunum, (I) Crypt length of ileum, (J) Villus/Crypt analysis of duodenum. (K) Villus/Crypt analysis of jejunum, (L) Villus/Crypt analysis of ileum. The unpaired t-test was used to determine whether differences existed between the two groups, *P < 0.05. Data are shown as mean ± SEM (n = 6).