Table 1. Search strategy used for electronic databases .

Database	Number of papers	Search Strategy
PubMed	18	(Pomegranate[MeSH Terms] OR Pomegranate[Title/Abstract] OR Pomegranates[Title/Abstract] OR "Punica granatum"[Title/Abstract] OR "pomegranate juice"[Title/Abstract] OR "Pomegranate extract"[Title/Abstract] OR Punicaceae[Title/Abstract] OR punica[Title/Abstract] OR granatum[Title/Abstract]) AND (Osteoarthritis[MeSH Terms] OR Osteoarthritis[Title/Abstract] OR Osteoarthritides[Title/Abstract] OR Osteoarthrosis[Title/Abstract] OR Osteoarthroses[Title/Abstract] OR "Arthritis, Degenerative"[Title/Abstract] OR "Arthritides, Degenerative"[Title/Abstract] OR "Degenerative Arthritides"[Title/Abstract] OR "Degenerative Arthritis"[Title/Abstract] OR Arthrosis[Title/Abstract] OR Arthroses[Title/Abstract] OR "Osteoarthrosis Deformans"[Title/Abstract])
Scopus	45	( TITLE-ABS-KEY ( pomegranate ) OR TITLE-ABS-KEY ( pomegranates ) OR TITLE-ABS-KEY ( "Punica granatum" ) OR TITLE-ABS-KEY ( "pomegranate juice" ) OR TITLE-ABS-KEY ( "Pomegranate extract" ) OR TITLE-ABS-KEY ( punicaceae ) OR TITLE-ABS-KEY ( punica ) OR TITLE-ABS-KEY ( granatum ) ) AND ( TITLE-ABS-KEY ( osteoarthritis ) OR TITLE-ABS-KEY ( osteoarthritides ) OR TITLE-ABS-KEY ( osteoarthrosis ) OR TITLE-ABS-KEY ( osteoarthroses ) OR TITLE-ABS-KEY ( "Arthritis, Degenerative" ) OR TITLE-ABS-KEY ( "Arthritides, Degenerative" ) OR TITLE-ABS-KEY ( "Degenerative Arthritides" ) OR TITLE-ABS-KEY ( "Degenerative Arthritis" ) OR TITLE-ABS-KEY ( arthrosis ) OR TITLE-ABS-KEY ( arthroses ) OR TITLE-ABS-KEY ( "Osteoarthrosis Deformans" ) )
ISI	27	(TS = (pomegranate) OR TS = (pomegranates) OR TS = ("Punica granatum") OR TS = ("pomegranate juice") OR TS = ("Pomegranate extract") OR TS = (punicaceae) OR TS = (punica) OR TS = (granatum)) AND (TS = (Osteoarthritis) OR TS = (Osteoarthritides) OR TS = (Osteoarthrosis) OR TS = (Osteoarthroses) OR TS = ("Arthritis, Degenerative") OR TS = ("Arthritides, Degenerative") OR TS = ("Degenerative Arthritides") OR TS = ("Degenerative Arthritis") OR TS = (Arthrosis) OR TS = (Arthroses) OR TS = ("Osteoarthrosis Deformans"))
Embase	48	('pomegranate'/exp OR pomegranate:ti,ab,kw OR pomegranates:ti,ab,kw OR 'punica granatum':ti,ab,kw OR 'pomegranate juice'/exp OR 'pomegranate juice':ti,ab,kw OR 'pomegranate extract'/exp OR 'pomegranate extract':ti,ab,kw OR punicaceae:ti,ab,kw OR 'punica'/exp OR punica:ti,ab,kw OR granatum:ti,ab,kw) AND ('osteoarthritis'/exp OR osteoarthritis:ti,ab,kw OR osteoarthritides:ti,ab,kw OR osteoarthrosis:ti,ab,kw OR osteoarthroses:ti,ab,kw OR 'arthritis, degenerative':ti,ab,kw OR 'arthritides, degenerative':ti,ab,kw OR 'degenerative arthritides':ti,ab,kw OR 'degenerative arthritis':ti,ab,kw OR arthrosis:ti,ab,kw OR arthroses:ti,ab,kw OR 'osteoarthrosis deformans':ti,ab,kw)
Proquest	2	(MAINSUBJECT(Pomegranate) OR AB(Pomegranate) OR TI(Pomegranate) OR mainsubject.Exact("pomegranates") OR AB(Pomegranates) OR TI(Pomegranates) OR mainsubject.Exact("punica granatum") OR AB("Punica granatum") OR TI("Punica granatum") OR MAINSUBJECT("pomegranate juice") OR AB("pomegranate juice") OR TI("pomegranate juice") OR MAINSUBJECT("Pomegranate extract") OR AB("Pomegranate extract") OR TI("Pomegranate extract") OR mesh.Exact("Punicaceae") OR mainsubject.Exact("punicaceae") OR AB(Punicaceae) OR TI(Punicaceae) OR MAINSUBJECT(punica) OR AB(punica) OR TI(punica) OR MAINSUBJECT(granatum) OR AB(granatum) OR TI(granatum)) AND (mesh.Exact("Osteoarthritis") OR mainsubject.Exact("osteoarthritis") OR AB(Osteoarthritis) OR TI(Osteoarthritis) OR MAINSUBJECT(Osteoarthritides) OR AB(Osteoarthritides) OR TI(Osteoarthritides) OR MAINSUBJECT(Osteoarthrosis) OR AB(Osteoarthrosis) OR TI(Osteoarthrosis) OR MAINSUBJECT(Osteoarthroses) OR AB(Osteoarthroses) OR TI(Osteoarthroses) OR MAINSUBJECT("Arthritis, Degenerative") OR AB("Arthritis, Degenerative") OR TI("Arthritis, Degenerative") OR MAINSUBJECT("Arthritides, Degenerative") OR AB("Arthritides, Degenerative") OR TI("Arthritides, Degenerative") OR MAINSUBJECT("Degenerative Arthritides") OR AB("Degenerative Arthritides") OR TI("Degenerative Arthritides") OR MAINSUBJECT("Degenerative Arthritis") OR AB("Degenerative Arthritis") OR TI("Degenerative Arthritis") OR MAINSUBJECT(Arthrosis) OR AB(Arthrosis) OR TI(Arthrosis) OR MAINSUBJECT(Arthroses) OR AB(Arthroses) OR TI(Arthroses) OR MAINSUBJECT("Osteoarthrosis Deformans") OR AB("Osteoarthrosis Deformans") OR TI("Osteoarthrosis Deformans")