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. 2022 Jan 5;12:803633. doi: 10.3389/fimmu.2021.803633

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Copyright © 2022 Nie, Fang, Chen, Aidina, Qiu, Zhao, Liu, Sun, Li, Zhong, Li and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ROC curves for IL-6 and CCL13 concentrations between patients with late-life depression and amnestic mild cognitive impairment. (A) Receiver operating characteristic curve for combining orientation and short-term memory scores to discriminate between the aMCI and LLD groups. (B) Receiver operating characteristic curve for combining IL-6 and CCL13 to discriminate between the aMCI and LLD groups. (C) Receiver operating characteristic curve for combining the four parameters above to discriminate between the aMCI and LLD groups. AUROC, area under the receiver operating characteristic curve; aMCI, amnestic mild cognitive impairment; LLD, late-life depression; IL-6, interleukin-6; CCL13, C-C chemokine ligand 13. The AUROC curves result from a logistic regression model adjusted for age, sex, and education. ROC, receiver operating characteristic.