Table 2.
Comparison of demographic characteristics and cognitive function between patients with late-life depression (LLD), subjects with amnestic mild cognitive impairment (aMCI), and normal controls (NC).
| aMCI (n = 23) | LLD (n = 23) | NC (n = 23) | Statistics | |
|---|---|---|---|---|
| Clinical demographic data | ||||
| Age | 73.0 (4.5) | 71.9 (5.7) | 72.5 (0.8) | 0.665 |
| Years of education | 13.0 (3.4) | 11.2 (2.9)# | 15.2 (2.2)#& | <0.01 |
| Gender (male:female) | 10:13 | 8:15 | 9:14 | 0.833 |
| Lifestyle (Y:N) | ||||
| Smoking | 5:18 | 3:20 | 3:20 | 0.649 |
| Drinking | 6:17 | 4:19 | 4:19 | 0.097 |
| Tea drinking habits | 13:10 | 5:18*# | 12:11 | 0.024 |
| Regular exercise | 21:2 | 6:17*# | 17:6 | <0.01 |
| Global Cognitive scales | ||||
| C-MoCA score | 20.8 (2.6) | 18.8 (6.1) | 26.3 (2.1)#& | <0.01 |
| WMDS score | 12.1 (2.8) | 13.4 (3.1) | 16.6 (3.3)#& | <0.01 |
| CFT score | 6.7 (2.5) | 5.5 (3.6) | 10.0 (4.2)#& | <0.01 |
| COWAT score | 12.1 (3.4) | 9.3 (3.5)# | 14.8 (3.3)#& | <0.01 |
| Geriatric Depression Scale | 7.0 (3.9) | 22.0 (4.6)*# | 5.1 (2.7) | <0.01 |
All values, except sex, anti-inflammatory medication, and lifestyle, are expressed as mean ± SD.
aMCI, amnestic mild cognitive impairment; LLD, late-life depression; NC, normal controls; C-MoCA, Chinese version of Montreal Cognitive Assessment; WMDS, Wechsler Memory Digit Span; CFT, Category Fluency Test; COWAT, Controlled Word Association Test.
*Significantly different from controls (p < 0.05).
#Significantly different from aMCI group (p < 0.05).
&Significantly different from LLD group (p < 0.05).