Table 3.
Level of inflammatory protein concentration in controls and patients.
| aMCI (n = 23) | LLD (n = 23) | NC (n = 23) | P | |
|---|---|---|---|---|
| TNF-α (pg/ml) | 5.2 (1.8) | 8.7 (16.8) | 5.5 (0.9) | 0.280 |
| CCL1 (pg/ml) | 1.7 (0.9) | 1.6 (0.8) | 1.4 (0.5) | 0.578 |
| CXCL8 (pg/ml) | 3.2 (2.2) | 2.3 (1.7) | 3.5 (2.8) | 0.361 |
| CCL7 (pg/ml) | 20.3 (16.9) | 13.6 (13.1) | 17.7 (15.8) | 0.282 |
| MIP2 (pg/ml) | 194.8 (140.4) | 180.6 (260.8) | 268.9 (259.4) | 0.249 |
| IL-1β (pg/ml) | 3.7 (1.7) | 4.5 (2.7) | 3.3 (2.5) | 0.175 |
| IFN-γ (pg/ml) | 26.6 (10.4) | 24.9 (6.0) | 24.2 (6.4) | 0.741 |
| CCL20 (pg/ml) | 60.4 (29.5) | 84.1 (117.1) | 64.3 (54.6) | 0.509 |
| CCL24 (pg/ml) | 550.5 (224.8) | 446.4 (260.2) | 553.1 (292.4) | 0.050 |
| CCL3 (pg/ml) | 133.8 (32.5) | 127.4 (41.5) | 130.3 (49.4) | 0.955 |
| CCL8 (pg/ml) | 279.5 (16.7) | 278.4 (13.1) | 275.7 (14.9) | 0.557 |
| IL-4 (pg/ml) | 29.2 (6.5) | 28.3 (5.0) | 27.5 (5.9) | 0.663 |
| CCL19 (pg/ml) | 115.9 (38.8) | 158.4 (143.9) | 114.4 (64.6) | 0.668 |
| IL-2 (pg/ml) | 4.0 (1.9) | 3.3 (2.5) | 3.6 (2.2) | 0.118 |
| CXCL9 (pg/ml) | 588.1 (80.7) | 611.6 (81.4) | 613.2 (89.3) | 0.705 |
| CCL23 (pg/ml) | 421.5 (150.6) | 454.6 (216.4) | 458.5 (200.2) | 0.784 |
| VCAM-1 (ng/ml) | 1,210.8 (452.7) | 1,342.2 (594.8) | 1,138.4 (599.4) | 0.324 |
| CCL27 (pg/ml) | 508.8 (146.1) | 488.2 (138.0) | 508.5 (143.2) | 0.880 |
| CCL11 (pg/ml) | 85.4 (31.5) | 73.7 (17.4) | 76.5 (42.2) | 0.302 |
| CXCL5 (pg/ml) | 437.7 (308.0) | 339.4 (223.2) | 605.4 (481.5) | 0.209 |
| CXCL6 (pg/ml) | 164.8 (90.2) | 121.6 (62.7) | 221.0 (191.4) | 0.179 |
| CCL25 (pg/ml) | 172.9 (78.6) | 145.2 (61.9) | 205.2 (130.6) | 0.258 |
| CCL2 (pg/ml) | 216.3 (117.8) | 153.2 (72.5) | 186.2 (98.6) | 0.118 |
| CCL17 (pg/ml) | 171.0 (120.5) | 115.5 (46.7) | 151.1 (95.9) | 0.181 |
All values are expressed as mean ± SD.
aMCI, amnestic mild cognitive impairment; LLD, late-life depression; NC, normal controls; TNF-α, tumor necrosis factor-alpha; IL-1β, interleukin-1-beta; (MIP)-2, macrophage inflammatory protein-2; IFN-γ, interferon-γ-inducing factor; IL-2, interleukin-2; IL-4, interleukin-4; VCAM-1, vascular cell adhesion molecule-1; CCL1, C-C chemokine ligand 1; CCL2, C-C chemokine ligand 2; CCL3, C-C chemokine ligand 3; CCL7, C-C chemokine ligand 7; CCL8, C-C chemokine ligand 8; CCL20, C-C chemokine ligand 20; CCL24, C-C chemokine ligand 24; CCL11, C-C chemokine ligand 11; CCL17, C-C chemokine ligand 17; CCL19, C-C chemokine ligand 19; CCL23, C-C chemokine ligand 23; CCL25, C-C chemokine ligand 25; CCL27, C-C chemokine ligand 27; CXCL5, C-X-C chemokine ligand 5; CXCL5, C-X-C chemokine ligand 6; CXCL8, C-X-C chemokine ligand 8; CXCL9, C-X-C chemokine ligand 9.