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A photomicrograph shows a stroma of OSCC demonstrating numerous endothelial cells with strong positivity for CD44 (A). These vessels exhibit CD31 positivity (B) (arrow) but no immunoreactivity for D2-40 is seen (C) (arrow head). CD31+/ Podoplanin – blood vessels were also strongly positive for CD44. Immunoperoxidase stains for CD44 (a), CD31 (b), and D2-40 (c) (a) × 400 (b, c) × 200.
