Table 2.
The sensitivity and specificity of cluster-specific genes
|
Cluster |
Cluster-specific genes (single/sets) |
Identification dataset (1969 isolates) |
||
|---|---|---|---|---|
|
No. of isolates |
Sensitivity |
Specificity |
||
|
C1 |
Set of 4 genes |
288 |
100 |
99.94* |
|
C2 |
Set of 3 genes |
101 |
100 |
100 |
|
C3 |
Set of 3 genes |
744 |
100 |
99.59* |
|
C4 |
Set of 2 genes |
51 |
100 |
100 |
|
C5 |
Set of 3 genes |
62 |
100 |
100 |
|
C6 |
Set of 2 genes |
20 |
100 |
100 |
|
C7 |
Single gene |
10 |
100 |
100 |
|
C8 |
Set of 2 genes |
12 |
100 |
100 |
|
C9 |
Set of 2 genes |
4 |
100 |
100 |
|
C10 |
Single gene |
2 |
100 |
100 |
|
CSS |
Set of 5 genes |
427 |
100 |
99.87* |
|
CSD1 |
Set of 2 genes |
70 |
100 |
100 |
|
CSD8 |
Single gene |
7 |
100 |
100 |
|
CSD10 |
Single gene |
2 |
100 |
100 |
|
CSB12 |
Single gene |
8 |
100 |
100 |
|
CSB13 |
Single gene |
7 |
100 |
100 |
|
CSB13-atypical |
Single gene |
5 |
100 |
100 |
|
53 Sporadic EIEC lineages |
Single gene/lineage |
59 |
100 |
100 |
*A cluster-specific gene set specificity of less than 100% was due to at least one FP found in that set.