Table 1.

Association of miR-451 and miR-506 with clinicopathological features of breast cancer patients.

Parameters	N	miR-451 expression				miR-506 expression
		Low (n = 49)	High (n = 39)	χ 2	P	Low (n = 45)	High (n = 43)	χ 2	P
Age, years				0.947	0.330			1.366	0.243
≤40	32	20	12			19	13
>40	56	29	27			25	31
Tumor size, cm				1.741	0.187			1.092	0.296
≤3	36	18	18			16	20
>3	52	31	21			29	23
LNM				4.503	0.034			6.527	0.011
Negative	43	19	24			19	24
Positive	45	30	15			28	17
ER				3.215	0.073			1.31	0.252
Negative	34	23	11			20	14
Positive	54	26	28			24	30
PR				1.108	0.292			0.682	0.409
Negative	33	16	17			15	18
Positive	55	33	22			30	25
HER-2				0.485	0.486			0.158	0.691
Negative	51	30	21			29	22
Positive	37	19	18			18	19
TNM stage				4.946	0.026			4.632	0.031
I-II	47	21	26			19	28
III-IV	41	28	13			25	16

LNM, lymph node metastasis; ER, estrogen receptor; PR, progesterone receptor; HER-2, human epidermal growth factor receptor 2.