Figure. Neurodevelopmental Impairment at 22-26 Months’ Corrected Age in Children Born at 22-26 Weeks’ Gestational Age During 2013-2016.

A, Neurodevelopmental impairment (NDI) among 2458 children evaluated at 22-26 months’ corrected age. Mild or no NDI was defined as a Bayley Scales of Infant and Toddler Development, Third Edition (Bayley-III) cognitive composite score of 85 or higher, a Bayley-III motor composite score of 85 or higher, and Gross Motor Function Classification System (GMFCS)²⁵ level 0 or 1. Moderate NDI was defined as any of a Bayley-III cognitive composite score or motor composite score of 70 to 84 or GMFCS level 2 or 3. Severe NDI was defined by any of a Bayley-III cognitive composite score or motor composite score less than 70, GMFCS level 4 or 5, bilateral blindness, or severe hearing impairment (see Table 4 footnotes b and d for more details).

B, Death and NDI at 22-26 months’ corrected age among children born at 22-26 weeks’ gestational age who were actively treated at birth. Children born at 22-26 weeks’ gestational age were eligible for a follow-up assessment at 22-26 months’ corrected age. Proportions are shown for the 3500 children actively treated at birth who had died by 22-26 months’ corrected age or were seen at follow-up and evaluated for NDI. Active treatment was defined as intubation, surfactant therapy, respiratory support, chest compressions, epinephrine, volume resuscitation, blood pressure support, or parenteral nutrition²² (see Table 4 footnotes b and d for more details).