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. 2022 Jan 19;376:e066084. doi: 10.1136/bmj-2021-066084

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© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

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Fig 5 — Estimation of relative treatment effects on adverse events. Results are risk ratios (95% confidence intervals) between each pair of treatments from network meta-analysis. Comparisons are read from right to left. For example, the risk ratio for adverse events with tricyclic antidepressants (TCAs) compared with benzodiazepines (BZDs) is 1.02 (95% confidence interval 0.83 to 1.25). Bold font indicates statistical significance. GRADE certainty of evidence of each comparison is: light green=moderate; light red=low; dark red=very low. MAOI=monoamine oxidase inhibitor; NaSSA=noradrenergic and specific serotonergic antidepressant; NRI=noradrenaline reuptake inhibitor; SSRI=selective serotonin reuptake inhibitor; SNRI=serotonin-noradrenaline reuptake inhibitor