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PTX induces increased nuclear FOXO1 in MDA-MB-231 cells. (A) Localization of FOXO1 by western blotting. Lamin AC, a nucleus-specific marker, and β-actin were used as internal controls. (B) Localization of FOXO1 was detected by immunofluorescence staining (scale bar, 20 µm). PTX, paclitaxel; FOXO1, forkhead box transcription factor O1.
