Table 2. Desirability of Outcome Ranking (DOOR), Intention-to-Treat Population at First Outcome Assessment Visit.
| DOOR descriptiona | Course, No. (%) | Cumulative risk difference (95% CI)b | |
|---|---|---|---|
| Short | Standard | ||
| No. | 189 | 191 | |
| ACR with antibiotic-associated adverse effects | |||
| None (1) | 97 (51) | 107 (56) | −4.7 (−14.9 to 5.7) |
| Mild (2) | 47 (25) | 42 (22) | −1.8 (−10.6 to 7.0) |
| Moderate (3) | 14 (7) | 10 (5) | 0.4 (−7.5 to 8.2) |
| Severe (4) | 0 | 2 (1) | −0.7 (−8.5 to 7.1) |
| Persistent symptoms (5) | 11 (6) | 13 (7) | −1.7 (−8.2 to 4.8) |
| No ACR | |||
| With ED or clinic visit (6) | 2 (1) | 1 (<1) | −1.1 (−7.5 to 5.1) |
| With hospitalization (7) | 0 | 0 | −1.1 (−7.5 to 5.1) |
| Death (8) | 0 | 0 | −1.1 (−7.5 to 5.1) |
Abbreviations: ACR, adequate clinical response; ED, emergency department.
a
DOOR rank (1) represents the best possible outcome and DOOR rank (8) the worst.
b
Cumulative risk differences were calculated as follows: for i Σ [1-8], the difference in proportions of participants between treatment strategies with DOOR rank ≤ i was calculated and 95% CIs were estimated using the Newcombe method with continuity correction.