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. 2007 Apr 18;2007(2):CD004215. doi: 10.1002/14651858.CD004215.pub2

Yeh 1980.

Methods Cross‐over design, quasi randomized, sequence of study alternated. 
 Blinding of randomization ‐ no 
 Blinding of intervention ‐ no Complete follow up ‐ yes 
 Blinding of outcome measure ‐ no
Participants 10 infants BW 1200‐1820g (mean 1444+‐250g), GA 31‐34 wks (32.7+‐ 1.0 wks), AGA, 4‐15 days age. 
 15 sets of observations made, no details provided about multiple values on infants.
Interventions Cross‐over design, Single vs double walled incubator. 
 Infant own control, simultaneous measurements of IWL, VO2 under single walled incubator (Ohio Servo Care) and double walled incubator (Ohio Intensive Care). Study Period 3 hrs each condition, sequence of study condition alternated. Insensible water loss measurement using Potter bed scale.
Outcomes Insensible water loss, oxygen consumption and carbon dioxide production under two conditions. Heat balance was calculated from oxygen consumption. Total heat loss, heat storage, heat loss, heat loss were calculated from temperatures measured. Heart rate and respiratory rate were recorded every 30 minutes.
Notes Incubators in specific quiet area of nursery, 1m from wall farthest from the window.
Risk of bias
Bias Authors' judgement Support for judgement
Adequate sequence generation? Unclear risk Cross‐over design, quasi randomized, sequence of study alternated.
Allocation concealment? High risk Blinding of randomization ‐ no
Blinding? 
 All outcomes High risk Blinding of intervention ‐ no
Blinding of outcome measure ‐ no
Incomplete outcome data addressed? 
 All outcomes Low risk Complete follow up ‐ yes

Abdominal skin temperature was maintained by servocontrol at 36.5 C