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. Author manuscript; available in PMC: 2022 Jan 19.
Published in final edited form as: Biomacromolecules. 2016 Jul 27;17(8):2572–2581. doi: 10.1021/acs.biomac.6b00577

Figure 5. Contact activity of ADGs in human plasma.

Figure 5.

A: Absolute clotting time in human plasma. 10 μM ADGs + 100 ng/ml PLC are comparably procoagulant to 10 μM molecularly dissolved, long-chain polyP. 10 μM ADGs without trigger and 100 ng/ml PLC alone marginally reduce the time to clot compared to the control (with no activator present). Absolute clotting time is given by the fitted inflection point of a Boltzmann sigmoidal growth function ± S.E. of the averaged absorbance traces of each sample group (n=11). * represents p<0.05 for a two-sided t test compared to control (without activator). B: Clotting times given as percent reduction from the control.