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. 2021 Dec 29;25(4):225–231. doi: 10.5114/wo.2021.112037

Table 2.

Examples of clinical trials involving the combination of immunotherapy and anti-angiogenic treatment in ovarian cancer

Identifier Agent/Drug Study title Status
NCT02659384 Bevacizumab
Atezolizumab
Acetylsalicylic Acid
Anti-programmed cell death-1 ligand 1 (aPDL-1) antibody atezolizumab, bevacizumab and acetylsalicylic acid
in recurrent platinum resistant ovarian cancer
Active,
not recruiting
NCT03353831
Atezolizumab
Bevacizumab
Chemotherapy
Atezolizumab with bevacizumab and chemotherapy vs. bevacizumab and chemotherapy in early relapse ovarian cancer Recruiting
NCT03363867 Atezolizumab
Bevacizumab
Cobimetinib
BEACON – ABC in recurrent platinum resistant HGSOC Recruiting
NCT04361370 Olaparib
Pembrolizumab
Bevacizumab
Olaparib maintenance with pembrolizumab & bevacizumab in BRCA non-mutated patients with platinum-sensitive recurrent ovarian cancer Not yet recruiting
NCT03596281 Pembrolizumab
Bevacizumab
Pegylated Liposomal Doxorubicin
Pembrolizumab in combination with bevacizumab and pegylated liposomal doxorubicin in patients with ovarian cancer Not yet recruiting
NCT02853318 Pembrolizumab
Bevacizumab
Cyclophosphamide
Pembrolizumab, bevacizumab, and cyclophosphamide in treating patients with recurrent ovarian, fallopian tube, or primary peritoneal cancer Active,
not recruiting

Data from ClinicalTrials.gov.