Figure 2.

Class-switched RBD-specific MBC analysis

(A and B) Longitudinal (A) classical MBC levels (dotted line indicates the healthy control threshold) and (B) trends of classical MBC levels across three visits stratified by disease severity.

(C) Impact of disease severity on classical MBCs at visit 3.

(D) Number of class-switched RBD-specific MBCs per million B cells in each subset per visit.

(E) Percentages of MBC subsets within the class-switched RBD-specific MBC group across three visits stratified by disease severity (mean + SD of participants).

AM, activated memory; RM, resting memory; IM, intermediate memory; TLM, tissue-like memory (^∗∗p between 0.001 and 0.01;^∗p between 0.01 and 0.05).

Also see Figures S1–S3 and Table S1.