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. 2004 Jul 19;2004(3):CD004217. doi: 10.1002/14651858.CD004217.pub2

Stang 1988 A.

Methods RCT 
 Blinding of randomization ‐ can't tell 
 Blinding of intervention ‐ partial 
 Complete follow‐up ‐ can't tell 
 Blinding of outcome measurement ‐ can't tell
Participants 60 male NB; > 24 hr age; BW > 3000 g; 5 min Apgar > 7; uncomplicated delivery
Interventions 0.8 ml 1% lidocaine DPNB (n=20) 
 saline DPNB (n=20) 
 no treatment control (n=20) 
 5 min WT 
 *comparison is DPNB versus no treatment
Outcomes % time cry, modal behavior state, plasma cortisol
Notes ‐ all handling avoided for 2 hr prior 
 ‐ 1/2 had blood sample for cortisol at 30 min, 1/2 at 90 min 
 ‐ all received pacifiers and continuously soothed 
 ‐ procedure standardized to 3 periods 
 ‐ Gomco and Plastibell used at operator's discretion 
 ‐ adverse effects reported
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear