Table 1.
Demographic characteristics as a function of MCR status in the whole sample, and as a function of study site
| MCR (All cohorts) | Non-MCR (All cohorts) | MCR (CCMA) | Non-MCR (CCMA) | MCR (TASCOG) | Non-MCR (TASCOG) | MCR (GAIT) | Non-MCR (GAIT) | MCR (NCGG-SGS) | Non-MCR MCR (NCGG-SGS) | |
|---|---|---|---|---|---|---|---|---|---|---|
| N | 66 | 133 | 7 | 42 | 9 | 41 | 25 | 25 | 25 | 25 |
| Age in years; M (SD) | 70.74 (6.46) | 73.5 (4.08) | 74.69 (4.51) | 73.97 (1.91) | 77.45 (10.37) | 78.27 (0.92) | 71.01 (4.42) | 71.01 (1.40) | 66.96 (4.03) | 67.64 (0.49) |
| Sex; % female (N) | 45 (30) | 49 (65) | 57 (4) | 52 (22) | 0.53 (5) | 56 (23) | 32 (8) | 32 (8) | 52 (13) | 48 (12) |
| Education | ||||||||||
| 5–8 y; %(N) | 27 (18) | 14 (19) | 14 (1) | 0 (0) | 67 (6) | 32 (13) | 44 (11) | 24 (6) | 0 (0) | 0 (0) |
| 9–12 y; %(N) | 51 (34) | 37 (49) | 29 (20) | 17 (7) | 22 (2) | 44 (18) | 40 (10) | 28 (7) | 80 (20) | 68 (17) |
| ≥13 y;%(N) | 21 (14) | 49 (65) | 57 (4) | 83(35) | 11 (1) | 24 (10) | 4 | 48 (12) | 20 (5) | 32 (8) |
| Mild cognitive impairment; %(N) | 36 (24) | 0 (0) | 43 (3) | 0 (0) | 11 (1) | 0 (0) | 56 (14) | 0 (0) | 24 (6) | 0 (0) |
| Total intracranial volume, mm3; M | 1,463,730 | 1,480,482 | 1,399,811 | 1,396,063 | 145,563 | 1,593,316 | 152,648 | 113,843 | 1,378,136 | 1,370,648 |
| white matter lesion, mm3; Mdn | 2,663 | 2,538 | 2,853 | 2,322 | 6,861 | 4,238 | 2,626 | 1,613 | 2,035 | 2,232 |