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. 2022 Jan 19;10(1):e01682-21. doi: 10.1128/spectrum.01682-21

TABLE 4.

Demographic variables associated with Elizabethkingia anophelis bacteremia by strains belonging to the specific lineage and other strains in Changhua Christian Hospitala

Variable E. anophelis strains of dominant lineage (n = 226) Other E. anophelis strains (n = 62) P value
Age 73.4 71.9 0.456
Sex, male, n (%) 135 (59.7) 40 (64.5) 0.495
Duration of admission, median (IQR), days 56 (35.0–84.0) 44 (28.3–106.7) 0.057
Ward, n (%) 0.035
 ICU 79 (35.0) 29 (46.8)
 RCC 53 (23.5) 6 (9.7)
 RCW 46 (20.4) 11 (17.7)
 Ward 48 (21.2) 15 (24.2)
 OPD 0 (0) 1 (1.6)
Period of admission, n (%)
 2005−2010 0 (0) 31 (50.0) < 0.001
 2011−2015 38 (16.8) 19 (30.6)
 2016−2020 188 (83.2) 12 (19.4)
Charlson comorbidity index, median (IQR) 3 (2.0–4.0) 3 (2.0–6.0) 0.0939
Comorbidities, n (%)b
 Solid-organ tumor 35 (15.9) 15 (24.2) 0.132
 Diabetes mellitus 91 (40.3) 28 (45.2) 0.489
 Chronic pulmonary disease 41 (18.1) 12 (19.4) 0.827
 Chronic kidney disease 73 (32.3) 18 (29.0) 0.624
 Hematologic malignancy 8 (3.5) 6 (9.7) 0.047
 Dementia 24 (10.6) 12 (19.4) 0.066
 Connective tissue disease 8 (3.5) 1 (1.6) 0.441
 Chronic liver disease 32 (14.2) 13 (21.0) 0.192
 Steroid use 17 (7.5) 4 (6.5) 0.774
 Mechanical ventilation 177 (78.3) 29 (46.8) <0.001
Antimicrobial treatment, n (%)b
 No treatment 27 (11.9) 3 (4.8) 0.105
 Aminoglycoside 3 (1.3) 2 (3.2) 0.312
 Carbapenem 12 (5.3) 4 (6.5) 0.729
 Cephalosporin 13 (5.8) 7 (11.3) 0.129
 Glycopeptide 34 (15.0) 16 (25.8) 0.048
 Fluoroquinolone 24 (10.6) 20 (32.3) <0.001
 Minocycline 37 (16.4) 1 (1.6) 0.002
 Penicillinc 20 (8.8) 13 (21.0) 0.008
 Trimethoprim/sulfamethoxazole 149 (65.9) 43 (69.4) 0.613
Mortality, n (%)
 14-day mortality 75 (33.2) 10 (16.1) 0.009
 In hospital mortality 115 (50.9) 20 (32.2) 0.014
a

ICU, intensive care unit; RCC, respiratory care center; RCW, respiratory care ward; OPD, outpatient department.

b

May be multiple.

c

Includes ampicillin/sulbactam, piperacillin, piperacillin-tazobactam.