Scheme 2. Derivatization of the products. Conditions: (i) pyrrolidine (5.0 equiv.), MeCN, RT, 12 h; (ii) Pd(PPh3)4 (5.0 mol%), toluene, RT, 1 h; (iii) Pd2(dba)3 (5.0 mol%), PPh3 (20 mol%), pyridine (3.0 equiv.), MeCN, RT, 1 h; (iv) TMSCl (5.0 equiv.), MeOH, 50 °C, 6 h; (v) Pd(OAc)2 (4.0 mol%), acetaldoxime (10 equiv.), 1,4-dioxane, reflux, 1 h; (vi) tBuOAc (6.0 equiv.), conc. H2SO4 (10 μL), 40 °C, 2 h; (vii) BH3·SMe2 (3.0 equiv.), THF, 0 °C to RT, 19 h.
