TABLE V. Recently Developed Label-Based Optical Biosensors for Recognizing Other Viral Infections.
Application | Target | RE | Linker | Surface | Sensor | LOD | Sample | Ref. |
---|---|---|---|---|---|---|---|---|
Vaccinia virus detection | Whole virus | Ab | Cyanine 5 dye | Fluorescent |
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seeded throat culture swab specimens | [78] | |
SARS-CoV detection | N protein | RNA aptamer | QDs ProLinker™ | Glass chip | Fluorescent (On-chip) |
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Buffer | [79] |
AIV detection | H5N2 AIV | mAb | GPTMS SH-PEG Biotin Cy3-SA | ZnO nanorod | Fluorescent |
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Buffer | [80] |
HCV detection | HCV RNA | Nucleic acid probe | Thiol Citrate AuNPs cysteamine CTAB | Colorimetric/spectrophotometric | 4.57 IU/
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Clinical sample | [81] |
QDs: quantum dots, PEG: polyethyleneglycol, HCV: Hepatitis C virus