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. 2021 Feb 16;21(9):10219–10230. doi: 10.1109/JSEN.2021.3059970

TABLE V. Recently Developed Label-Based Optical Biosensors for Recognizing Other Viral Infections.

Application Target RE Linker Surface Sensor LOD Sample Ref.
Vaccinia virus detection Whole virus Ab Cyanine 5 dye Fluorescent Inline graphic pfu/ml seeded throat culture swab specimens [78]
SARS-CoV detection N protein RNA aptamer QDs ProLinker™ Glass chip Fluorescent (On-chip) Inline graphic mL−1 Buffer [79]
AIV detection H5N2 AIV mAb GPTMS SH-PEG Biotin Cy3-SA ZnO nanorod Fluorescent Inline graphic EID50mL−1 Buffer [80]
HCV detection HCV RNA Nucleic acid probe Thiol Citrate AuNPs cysteamine CTAB Colorimetric/spectrophotometric 4.57 IU/ Inline graphic Clinical sample [81]

QDs: quantum dots, PEG: polyethyleneglycol, HCV: Hepatitis C virus