Table 5.
Univariate and Multivariate Cox Regression Analyses
| Factor | Univariate | Multivariate | ||
|---|---|---|---|---|
| X2 | P-value | HR (95% CI) | P-value | |
| Sex (M vs F) | 0.169 | 0.681 | - | - |
| Age (≥ 65 vs< 65) | 0.879 | 0.348 | - | - |
| Pathological type (squamous cell carcinoma vs adenocarcinoma) | 0.135 | 0.713 | - | - |
| Clinical staging (stage III vs IV) | 5.497 | 0.019 | 1.701 (1.099–2.632) | 0.017 |
| Brain metastasis (yes vs no) | 0.027 | 0.868 | - | - |
| History of smoking (yes vs no) | 0.764 | 0.382 | - | - |
| EGFR mutation (yes vs no) | 1.134 | 0.287 | - | - |
| Body weight change (>5% vs ≤5%) | 0.004 | 0.947 | - | - |
| ECOG score (0 vs 1) | 0.068 | 0.795 | - | - |
Abbreviations: EGFR, epidermal growth factor receptor; ECOG, Eastern Cooperative Oncology Group; HR, hazard ratio; CI, confidence interval.