TABLE 2.
Outcome Data Grouped by Development of Venous Thromboembolism
| Outcome Variable | All Patients, n = 98 | VTE, n = 26 | No VTE, n = 72 | p |
|---|---|---|---|---|
| VTE | 26 (26.5) | 26 (100) | ||
| DVT | 17 (17.4) | 17 (65.4) | ||
| Proximal | 15 (88.2) | 15 (57.7) | ||
| Distal | 2 (11.8) | 2 (7.7) | ||
| Isolated PE | 5 (5.1) | 5 (19.2) | ||
| PE and proximal DVT | 4 (4.1) | 4 (15.4) | ||
| Renal replacement therapy | 27 (27.6) | 15 (57.7) | 12 (16.7) | < 0.001 |
| Major bleedinga | 11 (11.2) | 6 (23.1) | 5 (6.9) | 0.06 |
| Extracorporeal membrane oxygenation (venovenous) | 7 (7.1) | 5 (19.2) | 2 (2.8) | 0.01 |
| Inhospital death (%) | 50 (51.0) | 18 (69.2) | 32 (44.4) | 0.04 |
| Time from ICU admit to death (d) | 13 (8–17) | 14 (6–28) | 13 (9–16) | 0.61 |
| ICU length of stay (d) | 13 (7–21) | 23.5 (8–37) | 11.5 (7–15) | 0.01 |
| Hospital length of stay (d) | 14 (11–28) | 23.5 (8–42) | 13 (11–20) | 0.08 |
DVT = deep venous thrombosis, PE = pulmonary embolism, VTE = venous thromboembolism.
aClassified by International Society on Thrombosis and Haemostasis guidelines: nine patients were on therapeutic anticoagulation, one was on prophylactic anticoagulation, and one had a prolonged prothrombin time of unknown etiology; one of the patients on therapeutic anticoagulation received tissue plasminogen activator prior to the bleed due to clotting of the extracorporeal membrane oxygenation circuit.
Measures represent number (column percent) or median (interquartile range) as appropriate.