Table 1. Subject characteristics.
| Clearance (n = 12) | Persistence (n = 17) | ||||||
|---|---|---|---|---|---|---|---|
| Pre-Cle.1 | Post-Cle.1 | Per. TM-Pre.1,2 | Per. TM-Post1,3 | Early Per.1 | Late Per.1 | P-value4 | |
| dpi5 median (range) | 89.75 (21–644) | 163.25 (78–821) | 97.75 (62–642) | 162.75 (106–1023) | 101 (57–156) | 352 (170–642) | 0.6, >0.9 |
| Genotype | |||||||
| 1a | 5 | 7 | 8 | 9 | 9 | ||
| 1b | 2 | 0 | 2 | 1 | 1 | ||
| 2b | 1 | 4 | 2 | 2 | 2 | ||
| 3a | 4 | 1 | 0 | 1 | 0 | ||
| RNA IU mean (range) | 1.5e6 (25–10.8e6) | <20 (0-<20) | 2.4e6 (244–8.1e6) | 2.6e6 (5,620–7.5e6) | 3e6 (181–8.1e6) | 1.6e6 (439–7.8e6) | 0.2, <0.0001 |
| Analyzed sE2+ csBC median (range) | 76 (19–1012) | 79 (10–1227) | 102 (34–599) | 193 (52–959) | 102 (34–686) | 220 (37–1083) | |
1Cle. = Clearance, Per. = Persistence, TM-Pre = Time Matched to Pre-Clearance samples, TM-Post = Time matched to Post-Clearance samples.
211 of 12 and
39 of 12 time-matched (TM) Per. subjects overlap with Early or Late Per. (n = 13).
4Pre-Cle. vs Per. TM-Pre or Post-Cle. vs Per. TM-Post, respectively. Unpaired two-tailed Mann-Whitney U Test for non-normally distributed data by Shapiro-Wilk test was used.
5days post-infection.