Table 1. Characteristics of the qPCR positive and negative groups with patient clinical and laboratory data.
| Characteristic | Leptospirosis (N = 54) | Non-leptospirosis (N = 56) | Total (N = 110) | P-value |
|---|---|---|---|---|
| Male gender, n (%) | 44 (81.48%) | 45 (80.36%) | 89 (80.91%) | 0.88 |
| Age, years, Mean (SD) | 50.78 (16.71) | 51.75 (15.93) | 51.25 (16.26) | 0.82 |
| Days of fever until enrollment, Median (IQR) | 3 (3, 5) | 3 (2, 4) | 3 (2, 4) | *0.01 |
| Exposure to flood waters, n (%) | 47 (85.45%) | 40 (81.63%) | 87 (79.09%) | 0.18 |
| Exposure to animals, n (%) | 8 (14.55%) | 9 (18.37%) | 17 (15.45%) | 0.73 |
| Body temperature, Mean (SD) | 38.14 (1.20) | 38.16 (1.24) | 38.15 (1.21) | 0.97 |
| SBP, mm HG, Median (IQR) | 109.00 (96.00, 121.50) | 120.00 (101.00, 129.50) | 111.00 (100.00, 126.00) | *0.02 |
| DBP, mm Hg, Median (IQR) | 61.00 (58.00, 73.25) | 68.00 (60.00, 76.75) | 64.00 (60.00, 74.00) | 0.10 |
| Platelet (x 103/μL), Median (IQR) | 94500.00 (59500.00, 213250.00) | 132000.00 (68500, 194750.00) | 118500.00 (63000.00, 204000.00) | 0.70 |
| *WBC (x 103/μL), Median (IQR) | 10950.00 (8525.00, 14025.00) | 8600.00 (5375.00, 12250.00) | 10500.00 (6350.00, 13375.00) | *0.02 |
| Creatinine, mg/dL, Median (IQR) | 1.33 (1.00, 2.90) | 1.10 (0.86, 1.27) | 1.12 (0.94, 1.96) | *0.01 |
| *TB, g/dL, Median (IQR) | 1.40 (0.82, 3.30) | 0.90 (0.50, 2.35) | 1.18 (0.70, 2.90) | *0.02 |
| *DB, g/dL, Median (IQR) | 0.90 (0.46, 1.97) | 0.50 (0.24, 1.55) | 0.70 (0.30, 1.80) | *0.03 |
| *SGOT, U/L, Median (IQR) | 63.00 (41.50, 147.00) | 64.50 (39.50, 170.00) | 63.00 (41.00, 164.00) | 0.91 |
| *SGPT, U/L, Median (IQR) | 59.00 (31.50, 103.50) | 60.00 (33.00, 84.75) | 60.00 (32.50, 96.00) | 0.77 |
| Na, mEq/L, Median (IQR) | 135.00 (132.00, 138.00) | 135.00 (131.45, 139.00) | 135.00 (131.70, 139.00) | 0.71 |
| K, mEq/L, Median (IQR) | 3.77 (3.40, 4.26) | 3.50 (3.09, 3.90) | 3.63 (3.26, 4.01) | *0.01 |
| HCO3, mEq/L, Median (IQR) | 24.00 (20.15, 25.75) | 25.00 (22.25, 26.45) | 24.55 (21.73, 26.00) | 0.11 |
Abbreviations: WBC: white blood cell; TB: total bilirubin; DB: direct bilirubin; SGOT: serum glutamic oxaloacetic transaminase; SGPT: serum glutamic; pyruvic transaminase, Na: sodium; K: potassium; HCO: bicarbonate; DBP: diastolic blood pressure; SBP: systolic blood pressure. Continuous data are expressed as the mean, standard deviation (SD) or median shown with interquartile range (IQR). Categorical variables are expressed as numbers (%)
* represents P < 0.05.