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Tumor acidic microenvironment downregulated the expression of mitochondrial oxidative respiration-related gene miR-451a. (a) The functional enrichment analysis by g:Profiler software. (b) The expression of miR-199a-3p, miR-451a, miR-223-3p, miR-146-5p, and miR-21-5p detected by qRT-PCR. Error bars, mean ± SD from three independent experiments. ∗∗P < 0.01; ∗∗∗P < 0.001.
