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. 2022 Jan 12;2022:9948515. doi: 10.1155/2022/9948515

Table 3.

Forward conditional logistic regression analysis determining main independent “frontline” predictors of 30-day mortality.

OR (95% CI) p value AUC C-statistic p value
Model 1 Lactate 1.55 (1.42 to 1.69) <0.001 0.787 (0.745 to 0.828) <0.001
Model 2 Lactate 1.46 (1.34 to 1.6) <0.001 0.830 <0.001
Intubated 6.09 (3.9 to 9.6) <0.001 0.793 to 0.867)

Model 3 Lactate 1.48 (1.35 to 1.62) <0.001 0.858 (0.825 to 0.891) <0.001
Intubated 9.74 (5.8 to 16.33) <0.001
Age 1.06 (1.04 to 1.08) <0.001

Model 4 Lactate 1.28 (1.15 to 1.43) <0.001 0.868 (0.837 to 0.900) <0.001
Intubated 9.35 (5.55 to 15.74) <0.001
Age 1.06 (1.04 to 1.08) <0.001
BE 1.11 (1.05 to 1.17) <0.001

Model 5 Lactate 1.27 (1.13 to 1.42) <0.001 0.878 (0.850 to 0.907) <0.001
Intubated 78.34 (4.89 to 14.2) <0.001
Age 1.05 (1.04 to 1.07) <0.001
BE 1.11 (1.05 to 1.17) <0.001
LVEF-mild/N REF
LVEF-mod 1.88 (1.21 to 3.16) 0.017
LVEF-severe 2.18 (1.28 to 3.75) 0.004

Model 6 Lactate 1.25(1.12 to 1.41) <0.001 0.879 (0.851 to 0.908) <0.001
Intubated 7.4 (4.3 to 12.74) <0.001
Age 1.05 (1.04 to 1.07) <0.001
BE 1.10 (1.04 to 1.17) <0.001
LVEF-mild/N REF
LVEF-mod 1.84 (1.09 to 3.1) 0.022
LVEF-severe 1.98 (1.14 to 3.42) 0.015
SBP 0.99 (0.982 to 0.999) 0.024

N = 892 patients included in the analysis. J: variables included in the regression model: age, gender, cardiac arrest, ongoing resuscitation on admission, ECG on admission, intubated/ventilated on admission, LVEF category, SBP, pH, lactate, and BE, statistically significant increase in the AUC when compared to previous model, OR: odds ratio, CI: confidence interval, AUC: area under the curve, BE: base excess, LVEF: left ventricular ejection fraction, SBP: systolic blood pressure, and ECG: electrocardiogram.