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. 2021 Dec 9;23(1):bbab489. doi: 10.1093/bib/bbab489

Table 2.

Challenge participating system method comparison

Team (Continent Organization) Main algorithm Temporal and cross-sectional modeling consideration Pre-filling
Ping An [14] (A, I) LightGBM Multi-directional temporal and cross-sectional features
AstraZeneca [16] (E, P) MICE GP estimated trend features and summary statistics to augment cross-sectional features for MICE
Vanderbilt [17] (N, U) XGBoost Measurements from concurrent and pre- and post-three time-stamps Global mean, local mean, SVD and Soft-Impute
HKBU [20] (A, U) Fusion layer to combine RNN and MLP outputs Temporal features for RNN, cross-sectional features for MLP Temporal decay
Padova [21] (E, U) Weighted average of KNN and linear interpolation outputs Temporal features for linear interpolation, cross-sectional features for KNN
TSU [22] (N, U) Piecewise linear interpolation and non-linear extension of MICE Temporal features for linear interpolation, cross-sectional features for non-linear extension of MICE Linear interpolation for tests with over 0.5 correlation with time
DLUT [23] (A, U) KNN, Soft-Impute and nuclear norm matrix factorization No explicit modeling for temporal trends
NCSU [24] (N, U) Matrix factorization methods Regularization term for modeling temporal locality
Drexel [25] (N, U) Similarity weighting Time window based similarity to capture temporal locality
Buffalo/Virginia [26] (N, U) Fusion gate to combine RNN outputs Separate RNNs for temporal features of each test and for cross-sectional features
IBM [27] (N, T) XGBoost as the ensemble method Base models: linear model for temporal imputation; KNN, RF, MLP for cross-sectional imputation; and bi-directional GRU and LSTM for combined imputation
Iowa [28] (N, U) Ridge regression, LASSO or gradient boosting as the ensemble method Base models: spline basis functions for temporal imputation; RBF neural network for cross-sectional imputation; and bi-directional LSTM for combined imputation RBF interpolation

Continent: A – Asia, N – North America, E – Europe. Organization: I – Insurance, P – Pharmaceutical, U – University, T – Technology.