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. 2022 Jan 20;55(2):201–209. doi: 10.1016/j.immuni.2022.01.014

Figure 1.

Figure 1

Immune responses in mild and severe COVID-19

Characteristic differences between patients developing mild versus severe COVID-19 disease with delayed and imbalanced IFN-I responses, lymphopenia, and uncontrolled viral replication. Typical signs of mild versus severe COVID-19 in terms of cytokine production, inflammasome activation, and coagulopathy, as seen a number of population studies (Carvalho et al., 2021).