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. 2021 Dec 15;601(7893):404–409. doi: 10.1038/s41586-021-04237-0

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 5 — a, Heatmaps of STICR^E10 (left) and STICR^E14 (right) lineage coupling scores between pairs of cell types, clustered by correlation distance and linkage. Values range from positive (red, coupled) to negative (blue, anti-coupled). Light-grey lines link clusters across stages. Clonal groups are surrounded with grey lines and manually annotated (a-y). Astro, astrocyte; CGE, caudal ganglionic eminence; Ctx, neocortex; EAC, central extended amygdala; Excit, excitatory; Hip, hippocampus; IN, interneuron; Inhib, inhibitory; MGE, medial ganglionic eminence; NP, neuronal precursor; OB, olfactory bulb; Oligo, oligodendrocyte; OPC, oligodendrocyte precursor cell; PN, projection neuron; SPN, spiny projection neuron. b, Feature plots highlighting examples of clonal groups that are maintained (left), split (middle) or merged (right) on the UMAP plot for STICR^E10 and STICR^E14.