Table 2.
B.1.1.7 variant(NR-54,011) | B.1.351 variant (NR-54,008) | B.1.351 variant (NR-54,009) | P.1 variant(NR-54,982) | Fold difference in GE/TCID | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Dilution | TCID50/mL | Mean log GE/mL | GE/TCID50 ratio | Mean log GE/mL | GE/TCID50 ratio | Mean log GE/mL | GE/TCID50 ratio | Mean log GE/mL | GE/TCID50 ratio | RatioNR-54,011/ NR-54,008 | Ratio NR-54,011/ NR-54,009 | Ratio NR-54,011/ NR-54,982 |
1 | 28 | 6.25 | 65,189 | 4.63 | 1540 | 4.35 | 809 | 4.56 | 1296 | 42 | 81 | 50 |
2 | 2.8 | 5.19 | 55,963 | 3.83 | 2454 | 3.27 | 672 | 3.45 | 1020 | 23 | 83 | 55 |
3 | 0.28 | 4.00 | 36,169 | 2.51 | 1193 | 2.11 | 471 | 2.39 | 913 | 30 | 77 | 40 |
4 | 0.028 | 2.85 | 25,294 | 1.27 | 674 | 0.73 | 248 | 1.32 | 755 | 38 | 102 | 33 |
Average | NA | NA | 45,654 | NA | 1465 | NA | 550 | NA | 996 | 31 | 83 | 46 |
*Genome equivalents (GE)/mL were calculated from a standard curve plot of TCID50 vs GE with an R2 value of 0.99.