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. 2022 Jan 19;12:998. doi: 10.1038/s41598-021-03968-4

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© The Author(s) 2022, corrected publication 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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³¹P-MRS data from first study visit. [PCr] is expressed as a fraction of the mean value during the initial 2-min rest period. Data for ID participants appear as white circles; those for IR participants, black circles. Solid black bars indicate 5-min exercise periods. All participants completed the 3-W exercise bout. Subsequently, several participants ceased exercise prematurely due to fatigue: during the 4-W bout, one IR participant after 1050 s; during the 5-W bout, one ID participant after 1820s, one IR participant after 1720s, and another IR participant after 1775s. For illustrative purposes, recovery data for these participants are shifted to align with cessation of exercise in the other participants; an ‘early recovery’ artefact is thus apparent in the IR group near the end of the 4-W and 5-W bouts. The rest periods include data for all participants. Values are 30-s means; error bars show SE.