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. 2022 Jan 19;12:998. doi: 10.1038/s41598-021-03968-4

Table 4.

Variables measured at the point of volitional fatigue during incremental CPET.

Iron status Iron deficient (n = 13) Iron replete (n = 13) P-value (RM-ANOVA)
Intervention Iron (n = 7) Saline (n = 6) Iron (n = 7) Saline (n = 6)
Visit 1 2 1 2 1 2 1 2
Power, W 180 ± 49 181 ± 46 182 ± 52 178 ± 54 216 ± 42 212 ± 43 184 ± 45 186 ± 49

Iron status = 0.31

Visit & intervention = 0.62

Iron status, visit & intervention = 0.027

V˙o2, ml/kg 38.0 ± 11.3 38.0 ± 10.9 39.0 ± 8.2 36.1 ± 8.3 41.3 ± 7.7 41.4 ± 9.8 39.6 ± 4.7 39.3 ± 5.6

Iron status = 0.45

Visit & intervention = 0.10

Iron status, visit & intervention = 0.22

RER 1.15 ± 0.08 1.16 ± 0.09 1.14 ± 0.07 1.14 ± 0.06 1.15 ± 0.05 1.12 ± 0.02 1.12 ± 0.04 1.12 ± 0.06

Iron status = 0.40

Visit & intervention = 0.84

Iron status, visit & intervention = 0.33

V˙E, L/min 102 ± 42 98 ± 40 98 ± 21 100 ± 16 123 ± 33 121 ± 32 93 ± 26 96 ± 28

Iron status = 0.50

Visit & intervention = 0.11

Iron status, visit & intervention = 0.86

Oxygen pulse, ml/beat 12.4 ± 3.1 12.8 ± 3.1 13.0 ± 3.7 12.6 ± 3.5 14.9 ± 3.8 15.4 ± 3.9 13.1 ± 2.9 12.6 ± 2.8

Iron status = 0.34

Visit & intervention = 0.036

Iron status, visit & intervention = 0.89

RPE 18.6 ± 1.5 18.3 ± 1.1 18.0 ± 1.8 17.8 ± 2.6 19.0 ± 1.0 18.9 ± 1.1 18.3 ± 1.0 18.5 ± 1.0

Iron status = 0.37

Visit & intervention = 0.61

Iron status, visit & intervention = 0.82

P-values are given for: (i) the effect of baseline iron status; (ii) the interaction between visit and intervention (the effect of IV iron); and (iii) the interaction between baseline iron status, visit, and intervention (whether any effect of IV iron differed according to baseline iron status). Values are means ± SD. Statistically significant P-values appear in bold. RER, respiratory exchange ratio; V˙E, minute ventilation; oxygen pulse is defined as V˙o2 divided by heart rate; RPE, rating of perceived exertion.