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. 2022 Jan 19;13(1):67. doi: 10.1038/s41419-022-04517-1

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — A Heatmap of β cell identity genes in control and sodium butyrate (SB)-treated rat islets. B Heatmap of dedifferentiation markers. C Heatmap of non-β cell markers. D Heatmap of disallowed genes. E RT-qPCR analysis of β cell identity genes in rat islets incubated with 5 mM SP or 5 mM sodium propionate (SB) for 24 h. Data were given as mean ± SD for three separate experiments. *p < 0.05, **p < 0.01, and ***p < 0.001 vs control (CON) group.