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. 2022 Jan 19;12:965. doi: 10.1038/s41598-022-04956-y

Table 2.

Clinical background of patients with terminal heart failure.

Patient Sex Age Cause of heart failure NYHA Assist Other diseases Tissue used for
1 M 65 Ischemic dilated cardiomyopathy IIIA No ASD, atrial fibrillation and asthma Proteomics IHC PCR
2 F 60 Restrictive cardiomyopathy, due to amyloidosis IIIA No PAH, asthma, amyloidosis and myeloma Proteomics IHC PCR
3 F 64 Idiopathic dilated cardiomyopathy IIIB No PAH, valvular disease, atrial fibrillation, diabetes type II, hypertension, renal insufficiency, hypothyreosis and previous ovarian cancer Proteomics IHC PCR
4 M 27 Idiopathic dilated cardiomyopathy III Yes PAH, atrial fibrillation Proteomics PCR
5 M 66 Idiopathic dilated cardiomyopathy IIIA Yes PAH, previous stroke and diabetes type II IHC PCR
6 M 67 Ischemic cardiomyopathy IIIA Yes PAH, previous AMI, atrial fibrillation and renal insufficiency IHC PCR
7 M 45 Hypertrophic cardiomyopathy IIIB No PAH IHC PCR
8 M 39 Ischemic cardiomyopathy III No PAH, previous AMI, valvular disease, diabetes type I, mild retinopathy and nephropathy PCR
9 M 66 Dilated cardiomyopathy due to amyloidosis IIIB No Diabetes type II and PAH PCR
10 M 50 Ischemic dilated cardiomyopathy IIIA No Diabetes type II, hypertension, and previous stroke PCR
11 M 61 Hypertrophic cardiomyopathy III No Previous stroke, previous atrial fibrillation, previous Maze surgery, renal insufficiency, COPD PCR

Table summarizes the clinical background of the included patients that underwent cardiac transplantation due to heart failure. F = female, M = Male, NYHA = New York Heart Association, PAH = Pulmonary Arterial Hypertension, AMI = Acute Myocardial Infarction, ASD = Atrial Septum Deficiency, COPD = Chronic Obstructive Pulmonary Disease, Assist = mechanical assist (i.e. LVAD / BiVAD), LVAD = Left Ventricular Assist Device, Proteomics = Global Quantitative proteomics, IHC = Immunohistochemistry, PCR = Polymerase chain reaction.