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. 2022 Jan 19;12:991. doi: 10.1038/s41598-021-04679-6

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Relative abundance of Bacterial taxa significantly associated with the treatment. Results are discriminated by trial over time, shown as sampling point as in Fig. 1. Results are presented by Trial 1 (A) and Trial 2 (B). Control groups are depicted in salmon while treated groups are shown in blue. The body of the box plot represents the first and third quartiles of the distribution and the median line of abundance of all ASV assigned to the corresponding genera. The whiskers extend from the quartiles to the maximum or minimum data within 1.5× interquartile range, with outlayers beyond. ANOVA test P < 0.05 shows significant differences in microbial abundance of Butyricimonas before and after the dose of phages. This figure was generated using Phyloseq package in R v 1.2.5 (https://www.r-project.org/).