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Increased mPGES1 protein abundance is dependent upon activation of NCC. Western blot (WB) analysis of PGE2 synthesis enzymes in tissue of kidney cortex. (A) mPGES1, total Cox2 (both bands), and Cox1 (B) quantification. Statistical significance evaluated by two-way ANOVA (see text), followed by Tukey’s post hoc tests (*p < 0.05).
