TABLE 1.

MIC of 9 quinolones for 194 clinical M. abscessus isolates.

Antibiotics	MIC range (mg/L)	Number of isolates exhibiting the MIC (mg/L) of quinolones indicated										MIC50 (mg/L)a	MIC90 (mg/L)a
		0.25	0.5	1	2	4	8	16	32	64	>64
Sitafloxacin	0.25–4	12	66	80	31	4	1	0	0	0	0	1	2
Ciprofloxacin	1– > 64	0	0	1	8	58	69	29	12	14	3	8	32
Levofloxacin	2– > 64	0	0	0	1	6	39	62	50	28	8	16	64
Moxifloxacin	0.5–16	0	1	10	41	76	49	14	3	0	0	4	8
Nemonoxacin	1–32	0	0	8	30	68	55	26	6	0	1	4	16
Gatifloxacin	1–32	0	0	5	27	83	50	25	5	0	0	4	16
Delafloxacin	32– > 64	0	0	0	0	0	0	0	3	23	168	>64	>64
Garenoxacin	32– > 64	0	0	0	0	0	0	0	1	18	168	>64	>64
Sparfloxacin	1– > 64	0	0	2	6	10	28	70	44	26	8	16	64

^aMIC₅₀ and MIC₉₀: the concentrations at which 50 and 90% of the clinical isolates tested, respectively, were inhibited.