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. 2022 Jan 6;12:795232. doi: 10.3389/fimmu.2021.795232

Figure 1.

Figure 1

Cytotoxicity of QDs on the respiratory system. The picture illustrates that QDs entered the endo-lysosomal system and then are released into cytoplasm, resulting in cell membrane damages, depolymerization or disruption of cytoskeleton, ROS generation, mitochondrial damages, ER stress, DNA damage, and apoptosis. Besides, QDs-induced ROS promotes mitochondrial damages, ER stress, and apoptosis. Full lines represent the situation demonstrated and dotted lines represent our deductions.