Table 3.
Prevalence of selenium deficiency among women of reproductive age (WRA) and school-aged children (SAC) participating in the AHHA trial.
| Control | Intervention | ||||
|---|---|---|---|---|---|
| Baseline, n (%) | Endline, n (%) | Baseline, n (%) | Endline, n (%) | Relative risk (95% CI) | |
| Prevalence of Se deficiency, GPX3 | |||||
| WRA | 83/89 (93.3) | 85/88 (96.6) | 81/88 (92.1) | 6/88 (6.8) | 0.07 (0.03, 0.15) |
| SAC | 84/87 (96.6) | 81/83 (97.6) | 86/86 (100) | 17/88 (19.3) | 0.20 (0.13, 0.30) |
| Prevalence of Se deficiency, DIO | |||||
| WRA | 62/89 (69.7) | 63/88 (71.8) | 58/88 (65.9) | 1/88 (1.1) | 0.02 (0.002, 0.112) |
| SAC | 77/87 (88.5) | 77/83 (92.7) | 77/86 (89.5) | 2/88 (2.8) | 0.02 (0.006, 0.097) |
| Prevalence of Se deficiency, KD | |||||
| WRA | 3/89 (3.4) | 0/88 (0) | 4/88 (4.6) | 0/88 (0) | NA |
| SAC | 5/87 (5.8) | 3/83 (3.6) | 11/86 (12.8) | 0/88 (0) | NA |
Deficiency is defined by thresholds of serum selenium concentration in adults for the optimal expression of glutathione peroxidase (GPX3; >84.9 mg L−1) and iodothyronine deiodinase (DIO; >64.8 mg L−1), and increased risk of Keshan Disease (KD, <30 mg L−1). Thresholds based on Thomson (30).