TABLE 2.
Subgroup analysis of miRNA-modified exosomes therapies on locomotor score.
| Subgroup | SMD, 95CI | I2 (%) | p value | |
| Blinding | ||||
| Yes(n = 6) | 4.64(3.66–5.63) | 38 |
|
0.15 |
| No(n = 6) | 3.33(2.48–4.17) | 48 | 0.08 | |
| Random | ||||
| Yes(n = 10) | 4.18(3.25–5.10) | 57 | 0.01 | |
| No(n = 2) | 4.33(2.78–5.88) | 0 | 0.34 | |
| Time | ||||
| Immediate(n = 4) | 3.22(2.25–4.19) | 0 | 0.52 | |
| Delay(n = 7) | 4.77(3.58–5.96) | 62 | 0.02 | |
| Dose | ||||
| 100 μg(n = 4) | 4.81(3.50–6.13) | 60 | 0.06 | |
| 200 μg(n = 5) | 4.39(2.56–6.21) | 63 | 0.03 | |
| Other(n = 3) | 3.39(2.27–4.51) | 0 | 0.75 | |
| Model | ||||
| Compression(n = 3) | 4.52(3.18–5.86) | 0 | 0.56 | |
| Contusion(n = 8) | 4.29(3.11–5.47) | 64 | <0.01 |