TABLE 1.
Characteristics of K210011 and corresponding transconjugants.
| Strain | Gene | MIC (mg/L) |
||||||||||||||
| IMP | MEM | ETP | CMZ | CAZ | CTX | TZP | SCF | CAV | FEP | PB | TGC | CIP | AK | ATM | ||
| K210011 |
blaIMP–4 blaKPC–2 blaNDM–1 |
4 | 16 | 64 | >128 | >128 | >128 | >256/4 | >256/128 | >64/4 | >64 | 1 | ≤0.25 | ≤1 | ≤4 | 64 |
| EC600 | / | ≤ 1 | ≤1 | ≤2 | ≤ 2 | ≤2 | ≤4 | ≤ 8/4 | ≤8/4 | ≤ 0.5/4 | ≤4 | ≤0.5 | ≤ 0.25 | ≤1 | ≤4 | ≤ 4 |
| TC-1 |
blaKPC–2 blaNDM–1 |
2 | 2 | 8 | 16 | >128 | 64 | 128/4 | 128/64 | >64/4 | 16 | ≤ 0.5 | ≤0.25 | ≤ 1 | ≤4 | 32 |
| TC-2 |
blaNDM–1 blaIMP–4 |
4 | 8 | 64 | >128 | >128 | 128 | 64/4 | >256/128 | >64/4 | 64 | ≤ 0.5 | ≤0.25 | ≤ 1 | ≤4 | ≤4 |
| TC-3 |
blaIMP–4 blaKPC–2 blaNDM–1 |
8 | 8 | 16 | >128 | >128 | >128 | 256/4 | >256/128 | >64/4 | >64 | ≤ 0.5 | ≤0.25 | ≤ 1 | ≤4 | 64 |
IMP, imipenem; MEM, meropenem; ETP, ertapenem; CMZ, cefmetazole; CAZ, ceftazidime; CTX, cefotaxime; TZP, piperacillin/tazobactam; SCF, sulbactam/cefopcrazone; CAV, ceftazidime/avibactam; FEP, cefepime; PB, polymyxin B; TGC, tigecycline; CIP, ciprofloxacin; AK, amikacin; ATM, aztreonam; TC-1, TC-2, TC-3, transconjugants of K210011.