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. 2022 Jan 6;12:721951. doi: 10.3389/fphys.2021.721951

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Copyright © 2022 Musolino, Tomà, De Rose, Pitaro, Boccuzzi, De Santis, Morello, Supino, Villani, Valentini and Buonsenso.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Grayscale lung ultrasound examination (transverse scan between intercostal fields; linear probe with 12 MHz frequency) of a 4-year-old boy with viral pneumonia – due to Coronavirus (non-COVID-19), Bocavirus, and Metapneumovirus coinfection- requiring respiratory assistance with High- flow nasal oxygen at the pediatric department. It shows sonographic interstitial syndrome (SIS) which is characterized by blurred, uneven, coalescent B-lines and white lung; irregular pleural line (arrows); reduced pleural sliding; multifocal inhomogeneous involvement; subpleural microconsolidations (generating pseudo-B-lines) (arrowheads).