FIGURE 3.

Genetic organization of the tetra-resistance regions found in food-borne isolates of the European monophasic clone. The alignment was created with EasyFig BLASTn including the tetra-resistance regions of strains 105/7/03 (accession number HQ331538, shown above) and 07-2006 (accession number KR856283; shown below) for comparison. The open reading frames (ORFs) are represented by arrows pointing to the direction of transcription and having different colors according to their origin or roles: white, chromosomal ORFs of the S. Typhimurium LT2 chromosome (named according to accession number NC_003197); red, resistance; blue, DNA mobility, with the tnpA gene of IS26 shown in dark blue; yellow, plasmid replication genes; pale orange, other roles. The gray shading between the structures connects regions of nucleotide sequence similarity ranging from 97 to 100%, according to the scale shown at the lower right part of the figure.