Table 3.

Studies that investigated employment-related outcomes in patients with MS within different levels of cognitive function.

First author	Country	Population	Main results
			Outcomes	Higher SDMT	Lower SDMT
Campbell et al. (25)	UK	62	Employment rate	60–80: 100% 50–60: ~60%	40–50: ~45% 30–40: ~20% 20–30: ~0%
Fraser et al. (28)	US	95	OR for fully employed vs. unemployed for a 1 SD difference in measure	SDMT written – 1.76 (0.89–3.53) SDMT oral – 1.46 (0.75–2.83)
Morrow et al. (27)	US	97	Adjusted OR was 4.2 (95% CI, 1.2–14.8) of a deterioration in employment (paid disability benefits or a reduction in working hours) based on a change of SDMT by 4.0

CI, confidence intervals; OR, odds ratio; SDMT, Symbol Digit Modalities Test. Bold values shows the estimate.