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. 2022 Jan 6;12:737211. doi: 10.3389/fneur.2021.737211

Table 7.

Studies that investigated work ability-related outcomes in patients with MS within different levels of cognitive function.

First author Country Population Main results
Outcomes Higher SDMT Lower SDMT
Chruzander et al. (30) Sweden 114 Proportion not on full-time disability pension No impairment: 57% Impaired cognitive function: 43%
Glanz et al. (31) US 377 Pearson correlation coefficient (95% CI) between SDMT and absenteeism 0.08 (0.18– 0.002)
Regression coefficient (95% CI) for absenteeism (adjusted) 0.09 (0.25–0.02)
Pearson correlation (95% CI) between SDMT and presenteeism 0.08 (0.18–0.03)
Regression coefficient (95% CI) for presenteeism (adjusted) 0.06 (0.08–0.20)
Kavaliunas et al. (33) Sweden 903 Work disability at baseline QIV: 98.5
QIII: 141.2
QII: 182.2
QI: 229.9
Adjusted IRR (95% CI) for disability after 1 year QIV: 1
QIII: 1.33 (1.111.60)
QII: 1.41 (1.18–1.70)
QI: 1.73 (1.42–2.10)
Adjusted IRR (95% CI) for disability after 3 years QIV: 1
QIII: 1.22 (1.03–1.45)
QII: 1.33 (1.12–1.58)
QI: 1.68 (1.40–2.02)
Predicted marginal mean of work disability (annual days) after 1 year QIV: 143
QIII: 191
QII: 203
QI: 247
Predicted marginal mean of work disability (annual days) after 3 years QIV: 154
QIII: 188
QII: 206
QI: 259

IRR, Incidence rate ratio; Q, quartile; SDMT, Symbol Digit Modalities Test. Bold values shows the estimate.