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. 2021 Dec 10;17(7):1545–1555. doi: 10.4103/1673-5374.330617

Figure 2.

Figure 2

EA improves functional recovery after ischemic stroke in terms of gait.

EA treatment was applied at the LI11 and ST36 acupoints in MCAO/R rats. ANA-12 was administered via intraperitoneal injection at 0.5 mg/kg once per day for 7 consecutive days. (A) Schematic of the CatWalk behavioral test. (B) Run duration. (C) Run average speed. (D, E) RF and RH body speed. (F, G) RF and RH stand time. (H, I) RF and RH swing speed. (J, K) RF and RH stride length. Data are presented as the mean ± SD (n = 9). #P < 0.05, ##P < 0.01, vs. sham group; *P < 0.05 vs. MCAO/R group (one-way analysis of variance followed by least significant difference post hoc test). The experiments were repeated three times. ANA-12: TrkB inhibitor; EA: electroacupuncture; LF: left forelimb; LH: left hindlimb; MCAO: middle cerebral artery occlusion and reperfusion; RF: right forelimb; RH: right hindlimb; TrkB: tyrosine kinase B.